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While much research has focused on the activation of stress response pathways during metabolic challenge, the mechanisms by which these pathways are attenuated once the stress subsides remain largely unexplored

10.1084/jem.20071416 J Exp Med

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Its primary pharmacological characterization was published in European Journal of Endocrinology (PMID 9849822), where the authors identified it as the first growth-hormone-secretagogue receptor (GHSR-1a) agonist achieving GH-release selectivity comparable to GHRH in animal models

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